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KMID : 0984720090410040253
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Infection and Chemotherapy
2009 Volume.41 No. 4 p.253 ~ p.257
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Recurrent Coccidioidomycosis Manifesting as Osteomyelitis in Korea
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Baek Ji-Hyeon
Shin So-Youn
Kim Chang-Oh
Choi Jun-Yong
Song Young-Goo
Cho Nam-Hoon
Park Eun-Young
Choi Hee-Kyung
Chin Bum-Sik
Han Sang-Hoon
Jung Yoon-Suk
Kim June-Myung
Jin Sung-Joon
Hong Jae-Won
Chae Yun-Tae
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Abstract
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Coccidioidomycosis is a fungal infection that results from inhaling the airborne arthroconidia of the Coccidioides species. It is an endemic disease in the southwest part of North America and rarely diagnosed in Korea. As tourism to endemic areas and the number of immunocompromised patients have been increasing, the incidence of this infection has increased in non-endemic areas. Treatment is usually successful with antifungal agents; however, recurrence is common. It is difficult to decide when to discontinue the antifungal treatment especially in non-endemic areas where doctors are not familiar with the disease. We report a case of recurrent coccidioidomycosis manifesting as osteomyelitis after the treatment of the patient for disseminated coccidioidal infection. The complement fixation test was a useful tool for the assessment of patient response and to evaluate suspected recurrence.
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KEYWORD
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Coccidioidomycosis, Recurrence, Osteomyelitis, Complement fixation test
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